Support for engineered floor joist

Do hangers for engineered floor joists supported at a structural member say a rim header, are all the holes required to be filled. Does anyone have any info about hangers and engineered floor joists?

Thanks

All of the major companies have sites with specs and tech documents

Simpson

APA

WIJMA

*(http://ilevel.com/)

*(http://www.lpcorp.com/ijoists/ijoists.aspx?medium=PPC&source=Google_AdWords&account=EWP&campaign=IJoists&ad_group=Misc&copy=ddav1)

there are many others if needed**

Generally, all holes should be filled with nails of the type and size specified by the hanger manufacturer.