Notch/holes for engineered I joists

It is my understanding that the chords cannot be modified for this type of floor joist. What about the web?

I found the answer:

It depends on many variables but, with the two notches in the one span, I think not:

and… (page 11, etc.)

**[FONT=MyriadDomtar2002-Bold]Cutting the Holes
[/FONT][FONT=MyriadDomtar2002-Bold][size=5][FONT=MyriadDomtar2002-Bold][size=5]• **[/size][/FONT][/size][/FONT][FONT=StoneSerif][size=1]Never drill, cut or notch the flange, or over-cut the web.