Any idea what this screw is for?

Do you guys have any ideas why this screw might be on the breaker?

Just guessing loose breaker and screw helps to hold it tight .

Those are typically seen on mains.

Breaker retainer screw used for some styles of backfed breakers. No issue.

If the CB is back fed it’s required by the NEC to have a screw, rivet, clip or some other means to keep it from being pulled out.

Really surprised Master Electrician, CMI, Roy Cooke didn’t know that! (No I’m not).

For the OP here’s the NEC reference: